Question

Cyclosporin A is produced by:

• A. \text{Trichoderma polysporum}
• B. \text{Monascus purpureus}
• C. \text{Bacillus thuringiensis}
• D. \text{Agrobacterium tumefaciens}

Hint:

When studying drugs and their sources, it is important to know the specific microorganism or organism responsible for the production. Cyclosporin A is a key example produced by fungi like \textit{Trichoderma polysporum}.

Answer 1

The Correct Option is A

Understanding Cyclosporin A
- Cyclosporin A is an immunosuppressive drug widely used in organ transplantation to prevent rejection by suppressing the immune response.
- It was first isolated from the fungus Trichoderma polysporum, which is known for producing secondary metabolites with medicinal properties.
Examining the given options
- Option 1 (Trichoderma polysporum) → Correct, as it is the actual source of Cyclosporin A.
- Option 2 (Monascus purpureus) → Incorrect, as it is used for producing statins (cholesterol-lowering drugs).
- Option 3 (Bacillus thuringiensis) → Incorrect, as it produces Bt toxin, used in pest-resistant crops.
- Option 4 (Agrobacterium tumifaciens) → Incorrect, as it is used in genetic engineering for plant transformation.
Conclusion
Since Trichoderma polysporum is the correct source of Cyclosporin A, the correct answer is Option (1).