Analyze the pairs by subtracting the second number from the first:
181 - 48 = 133
170 - 55 = 115
131 - 42 = 89
80 - 25 = 55
Observe the results:
133, 115, and 55 are all composite numbers (not prime), but 89 is a prime number.
Hence, the pair 131-42 is different because the difference 89 is prime, whereas the others are not.