Question:
Besides better aeration and mixing properties, what other advantages do stirred tank bioreactors have over shake flasks?
Besides better aeration and mixing properties, what other advantages do stirred tank bioreactors have over shake flasks?
Updated On: Oct 5, 2023
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Solution and Explanation
The shake flask method is used for small-scale production of biotechnological products in a laboratory. On the other hand, stirred tank bioreactors are used for the large-scale production of biotechnology products.
Stirred tank bioreactors have several advantages over shake flasks:
- Small volumes of culture can be taken out from the reactor for sampling or testing.
- It has a foam breaker for regulating the foam.
- It has a control system that regulates the temperature and pH.
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Concepts Used:
Biotechnology
Biotechnology is a vast field of biology that involves the creation, production, and modification of useful products for human welfare using both the technology and the execution of living organisms and their components. An agricultural engineer, Karoly Ereky, coined the word "biotechnology" in 1919, achieving him the title of "Father of Biotechnology."
Principles of Biotechnology:
Among many, the two core techniques that entitled the birth of modern biotechnology are :
- Genetic Engineering is one of the methods of direct modifications of an organism's genome (i.e., DNA and RNA). It requires the introduction of new genes into host species to escalate function or trait, hence altering the host organism's phenotype.
- Bioprocess Engineering is one of the methods of maintaining sterile conditions to facilitate the growth of large quantities of desired microbes and other eukaryotic cells for the development of new or modified biotechnological products such as enzymes, vaccines, antibiotics, and other biotechnological products.