Assertion (A) : In dihybrid crosses involving sex-linked genes in \(\textit{Drosophila}\), \(F_2\) generation of non-parental gene combinations are observed.
Reason (R) : Two genes present on different chromosomes show linkage and recombination in \(\textit{Drosophila.}\)
Assertion (A) states that in dihybrid crosses involving sex-linked genes in\( \textit{Drosophila}\), the \(F_2\) generation shows non-parental gene combinations. This is true. Sex-linked genes are located on the X chromosome. During meiosis in the \(F_1\) generation (which are heterozygous for these genes), recombination (crossing over) can occur between the sex chromosomes, leading to the formation of gametes with non-parental combinations of the linked genes. These non-parental combinations will be observed in the \(F_2\) generation.
Reason (R) states that two genes present on different chromosomes show linkage and recombination in\( \textit{Drosophila}\). This is false. Genes located on different chromosomes assort independently according to Mendel's law of independent assortment. Linkage occurs when genes are located on the same chromosome and tend to be inherited together. Recombination occurs due to crossing over between homologous chromosomes during meiosis, which can separate linked genes, but it doesn't apply to genes on different chromosomes in the context of linkage. Genes on different chromosomes exhibit independent assortment, resulting in non-parental combinations due to the random segregation of chromosomes. Therefore, Assertion (A) is true, but Reason (R) is false.
The sequence of nitrogenous bases in a segment of a coding strand of DNA is
5' – AATGCTAGGCAC – 3'. Choose the option that shows the correct sequence of nitrogenous bases in the mRNA transcribed by the DNA.
1. Perform a cross between two sickle cell carriers. What ratio is obtained between carrier, disease free and diseased individuals in F1 progeny? Name the nitrogenous base substituted, in the haemoglobin molecule in this disease.
2. Explain the difference in inheritance pattern of flower colour in garden pea plant and snap-dragon plant with the help of monohybrid crosses.
OR,
Explain with the help of well-labelled diagrams how lac operon operates in E. coli :
1. In presence of an inducer.
2. In absence of an inducer.
Study the pedigree chart given below, showing the inheritance pattern of blood group in a family:
Answer the following questions:
(a) Give the possible genotypes of individual 1 and 2.
(b) Which antigen or antigens will be present on the plasma membranes of the R.B.Cs of individuals ‘5’ and ‘8’?