Question

Assertion (A): Disulphide bridges help in stabilization of protein structure.
Reason (R): Sulphur forms disulphide bridges in the quaternary structure of proteins.

• A. and (R) are correct, and (R) is the correct explanation of (A).
• B. (A) and (R) are correct, but (R) is not the correct explanation of (A).
• C. (A) is correct, but (R) is not correct.
• D. (A) is not correct, but (R) is correct.

Hint:

Disulphide bonds are covalent bonds that stabilize protein folding, particularly in extracellular proteins like insulin and keratin.

Answer 1

The Correct Option is A

Step 1: Understanding Disulphide Bridges
- Disulphide bonds (\( S-S \) bonds) form between cysteine residues in proteins, providing stability.
- These bonds are important for tertiary and quaternary structures, preventing unfolding.
Step 2: Evaluating the Assertion and Reason
- (A) is correct: Disulphide bonds contribute to protein stability.
- (R) is correct: Sulphur indeed forms disulphide bonds, and these are crucial in higher-order structures.
- (R) correctly explains (A), making option (A) correct.