Question

Assertion (A): Aromatic primary amines cannot be prepared by Gabriel Phthalimide synthesis.
Reason (R): Ary1 halides do not undergo nucleophilic substitution reaction with the anion formed by phthalimide.

• (A) and (R) are true, and (R) is the correct explanation of (A).
• (A) and (R) are true, but (R) is not the correct explanation of (A).
• (A) is true, but (R) is false.
• (A) is false, but (R) is true.

Hint:

When preparing amines, remember that aromatic halides typically require stronger conditions or a different synthetic approach due to their stability.

Answer 1

The Correct Option is A

Gabriel Phthalimide synthesis involves nucleophilic substitution by the anion of phthalimide to form primary amines. However, aromatic halides are less reactive towards nucleophilic substitution because of their resonance stability. Therefore, Assertion (A) is true, and Reason (R) correctly explains the difficulty in preparing aromatic primary amines.