Step 1: Animal cells possess a centrosome, which contains centrioles involved in spindle formation during cell division.
Step 2: Plant cells lack centrosomes and centrioles.
Step 3: Plastids and large central vacuoles are characteristic of plant cells.
Step 4: Golgi bodies are present in both plant and animal cells.
Hence, the distinguishing feature is the presence of a centrosome in animal cells.