Aneuploidy refers to an abnormal number of chromosomes, which is not a multiple of the haploid set. This arises due to errors during chromosome segregation in meiosis.
Addition (B) and Deletion (C): These directly lead to aneuploidy. Nondisjunction, where chromosomes fail to separate correctly, can result in the addition or deletion of chromosomes in gametes.
Substitution (A): Involves replacing one nucleotide with another and does not change the chromosome number.
Translocation (D): Involves the transfer of a segment of a chromosome to a nonhomologous chromosome. While potentially causing other genetic disorders, balanced translocations do not directly cause aneuploidy because the total number of chromosomes remains the same.
Inversion (E): A segment of the chromosome is reversed end-to-end. This doesn’t change
the chromosome number.
Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.
Assertion A : The potential (V) at any axial point, at 2 m distance(r) from the centre of the dipole of dipole moment vector
\(\vec{P}\) of magnitude, 4 × 10-6 C m, is ± 9 × 103 V.
(Take \(\frac{1}{4\pi\epsilon_0}=9\times10^9\) SI units)
Reason R : \(V=±\frac{2P}{4\pi \epsilon_0r^2}\), where r is the distance of any axial point, situated at 2 m from the centre of the dipole.
In the light of the above statements, choose the correct answer from the options given below :