Question:

Aminoacylation of tRNA is essential for

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Aminoacylation of tRNA is the process when tRNA specific for the amino acid forms aminoacyl.

Updated On: Sep 15, 2022
  • replication of RNA
  • formation of peptide bond
  • splicing
  • initiation of transcription
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The Correct Option is B

Solution and Explanation

Aminoacylation of tRNA is the process when tRNA specific for the amino acid forms aminoacyl. Proteins are synthesized through 3 steps - initiation, elongation, and termination.  

  • The amino acid is linked to 3' - OH end of tRNA through its -COOH group. 
  • This process is important for protein synthesis through formation of peptide bonds between amino acids. 
  • For initiation, the ribosome first binds to mRNA at the start codon that is always recognized by the initiator tRNA.
  • The amino acids are activated in the presence of ATP and then linked to their tRNA.
  • The chargedt t RNA carries the amino acid and binds it to the specific codon on mRNA that codes for that particular amino acid. 
  • A bond is formed between this amino acid and the one present already. 
  • The free tRNA is released and is then able to carry another amino acid.

Hence, option B) 'formation of peptide bond' is correct.

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Concepts Used:

The Molecular Basis of Inheritance

DNA Replication:

DNA synthesis is commenced at particular points within the DNA strand referred to as ‘origins’, which are certain coding regions. There are numerous origin sites, and when replication of DNA starts, these sites are mentioned as replication forks. Within the replication, the complex is the enzyme DNA Helicase, so that they can be utilized as a template for replication. DNA Primase is another enzyme that's essential in DNA replication.

RNA:

Ribonucleic acid (RNA) is an essential biological macromolecule that exists all together in biological cells. It is principally involved in the synthesis of proteins, that carry the messenger instructions from DNA, which itself contains the genetic instructions needed for the event and maintenance of life. In some viruses, RNA, in spite of DNA, carries genetic information.

Genetic Code:

Genetic code is the term we use in the manner that the four bases of DNA--the A, C, G, and Ts--are strung together in a way that the ribosome, the cellular machinery, can read them and switch them into a protein. In the ordering, every three nucleotides during a row count as a triplet and code for one amino alkanoic acid.

Read More: Molecular Basis of Inheritance