Let's decode the relationship in the expression:
- "Q + R" means Q is the sister of R.
- "R - P" means R is the father of P.
- "P \times N" means P is the brother of N.
- "N - S" means N is the father of S.
From these relationships, we know that R is the father of P, and P is the brother of N. Therefore, R is the uncle of S.
Thus, the correct answer is (C) Uncle.